Technical Parameters |
No | Item | Description |
1 | Vessel System | Total volume:10-10000L, Max Working volume:70%
SUS 316 material tank body SUS304 jacket, stainless steel 316L tank cover, easy to observe the material; with temperature, pH, DO, defoaming, liquid level interface, inoculation port, feeding port;
The design pressure: P(inside)= 0.3Mpa, P(interlayer)=0.3Mpa, The polishing precision: Ra0.4~0.6,the ratio between diameter and height: 1:2.5 |
2 | Sterilization method | In situ steam automatic /manual sterilization, sterilization temperature 100-130℃, Sterilization can be stirred at the same time, can thoroughly sterilize the medium. |
3 | Aeration system | Configure one air intake (air) including: rotameter, mass flowmeter, 2-stage sterilization filter, non-return valve, etc., to ensure that the air enters the tank aseptically. Using an aerator (Ring Sparger & Microsparger) and Overlay to supply gases simultaneously Two-way ventilation is equipped with four-way gas (Air, O2, CO2, N2) mixed intake, mass flow meter (four-way TMFC automatic adjustment) to be able to supply different gas mixtures in these ways. |
4 | Agitation system | Mechanical sealing or Magnetic coupling stirring at the top of the fermenter;
Fermentation special blades, stirring form: 4x baffles. 1x comb type foam breaker., also according to fermentation the special requirements of the process are to replace different types of stirring paddles. Speed: 50~1000rpm±1%, stepless speed regulation. |
5 | Temperature control | Heat by thermostatic water tank and circulate by circulating pump, Temperature control: ambient +5℃-65℃;±0.1℃, display temperature: 0-150℃±0.1℃ |
6 | Airflow control | Automatic or manual adjustment, flow meter display; range:0.1-2.0vvm; |
7 | Antifoam control | Automatically check foam, automatically add antifoam by peristaltic pump. |
8 | Feeding control | Control by peristaltic pump switch, automatically feeding and computation. |
9 | pH control | Using intelligent PID control, high control accuracy, and it is not easy to fluctuate, peristaltic pump switch to control the flow of acid and alkali, automatic control, automatic measurement. The electrode can be sterilized repeatedly, and the calibration function is completely calibrated by the system software. |
10 | DO control | The DO value is controlled in association with the speed,replenishment, air flow (if configured) and other parameters. Control range: 0~150%, ±3% fermentation process sequence control (according to fermentation time, DO automatic variable control, at least 10 stages) |
11 | BioVita S Biology process controller | Control parameter: temp, pH, DO, antifoam, stirrer rev, feeding,etc |
12 | BioVita S Control System | BioVita S is an on-site controller designed for Siemens S7-1200 series PLC, offering a stable and versatile solution for automation, especially in manufacturing process control. Its modular design enables easy implementation of distributed configurations. The system features a 12-inch LCD touchscreen with an intuitive English menu, supporting direct on-site operation and data transmission to a host computer for analysis. Control Modes: - Manual: Adjust valve opening percentage - Automatic: Continuous or PID control - Sequential: Pre-set up to 10 control sections - Remote: PC-based segmentation control
- Correlation: DO control via speed, airflow, pressure, feeding; pH control via acid/alkali
Measurement Functions: -Supports pH, feeding, and anti-foam monitoring Data Processing: - Trend curve and batch report analysis - Historical data storage and USB export - Excel-compatible format System Protection & Customization: - Password protection for fermentation settings - Power failure recovery - Adjustable recording intervals
- Independent module-based parameter transmission for easy maintenance
Real-time Monitoring: -Displays system status, hardware conditions, and fault identification for pumps, heating, mixing, etc.
The system integrates Siemens S7 software and FORCE CONTROL, utilizing Siemens S1200 PLC for data collection and control. It ensures high precision, adaptability to various sensors, and robust anti-interference capabilities. |